HER2 and CD24 Emerge as Promising Radiotheranostic Targets in Endometrial Cancer

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  HER2 and CD24 Emerge as Promising Radiotheranostic Targets in Endometrial Cancer Introduction Endometrial cancer, the most common gynecological cancer in developed countries, has been steadily rising in incidence worldwide. While early-stage disease often responds well to surgery and conventional therapies, advanced and recurrent cases remain challenging to treat. Over the last decade, researchers have been exploring precision oncology strategies—approaches that target specific molecular markers in cancer cells to improve outcomes. Among these emerging strategies is radiotheranostics , a cutting-edge field that combines diagnostic imaging and targeted radionuclide therapy. The idea is simple yet powerful: use the same molecule to both detect and destroy cancer cells. Recent studies highlight two promising molecular candidates for radiotheranostic development in endometrial cancer— HER2 (human epidermal growth factor receptor 2) and CD24 , a cell surface glycoprotein. In t...
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Red Sox trade All-Star slugger Rafael Devers to Giants

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 In a surprising move, the Boston Red Sox have traded All-Star slugger Rafael Devers to the San Francisco Giants. The blockbuster deal was announced on Sunday, June 15, 2025.

The Giants acquired Devers in exchange for a package of players that includes pitchers Jordan Hicks and Kyle Harrison, along with prospects James Tibbs III and Jose Bello. The Giants will also be taking on the entirety of Devers' substantial contract, which was a 10-year, $313.5 million extension he signed in 2023.

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This trade comes amidst some reported tension between Devers and the Red Sox organization regarding his defensive position this season, particularly after the Red Sox signed third baseman Alex Bregman and asked Devers to move to designated hitter, and later to first base, which he declined.

Devers, a three-time All-Star and a key contributor to the Red Sox's 2018 World Series championship, was having a strong offensive season for Boston before the trade. He will now join a Giants team looking to bolster its offense as they contend in the competitive NL West.

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